Quantifying the transactivation activity, cell growth inhibitory activity, and mouse xenograft inhibitory activity of the 800 p53 mutants before and after ATO treatment
| MUTANT | RESCUABLE BY ATO? | FREQUENCY IN CANCER | STRUCTURAL INFORMATION | ACTIVITIES WITHOUT ATO | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Short (Full) |
Transcription activity |
Cell inhibitory activity |
Tumor suppressive activity |
Summary |
IARC (ranking) |
TCGA (ranking) |
Location |
Accessibility (score) |
Mutation type |
Temperature sensitivity (% cell died at 32℃) |
3D View |
Transcription activity |
Cell inhibitory activity |
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